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No. Jackson Jekyll is human, whose father was the original mad scientist. Jackson's alter monster ego is Holt Hyde, who loves music and is a DJ. So again no they are not brothers, Holt Hyde is Jackson Jekyll's ego.
He goes there because of his alter-ego,Holt Hyde. They relate to the whole Jekyll Hyde thing. Jackson is the normie (human) and Holt is the monster.
Actually Jackson Jekyll is a human, but when he over heats he becomes DJ Holt Hyde, I'm not exactly sure what Holt Hyde is, but he is classified as a monster.
Holt Hyde is the son of Dr. Jekyll/Mr. Hyde. He is the nighttime version of Jackson Jekyll. He, like his alter-ego, is voiced by Cindy RobinsonContents[show] PersonalityIn the Diaries, Holt's transformation into Jackson Jekyll normally occurs at sunrise and lasts until sunset. The change is apparently outside of his or Holt's control; Holt noted in his journal that when he was trying to see what the town was like during the day, he blacked out at the moment of sunrise.In the MH novels it is caused by temperatures be it from him getting hot from embarrassment to outside forces like a hot day.In the webisodes it seems to be music that causes Jackson's transformation rather than the time of day. This is first seen in "Hyde and Shriek".Despite not being aware of his true nature, there are times when Jackson's and Holt's memories and abilities leak over to the other. For example, in theDiaries Jackson is able to keep up with Deuce Gorgon
Jackson Jekkyl / Holt Hyde is the son of Dr Jekkyl and Mr Hyde therefore there are 2 separate dolls for him but they are the same person.