Some of them did. Ben Cartwright was married three times, all three wives met with misfortune and died. All the Cartwright men planned to marry at one time or another but only Little Joe married in the first episode of the last season. She also died.
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The Cartwright men were incredibably unlucky at love, repeatedly. Little Joe did get married, season 14, but of course she met with a terrible end, as all the women on the Ponderosa do. Hoss, Adam and Pa almost made it to the alter but didn't quite get there. Either their sweeties left or died.
Any woman that became interested in any of the Cartwrights either caught a fatal disease or had a fatal accident. Little Joe's wife caught a fatal disease.
the Cartwrights owned 1,000sq. miles.
I could find no tally of how many times the Cartwrights were shot. Considering most people live entire lives without gunplay, the Cartwrights have much more than average.
The Gamble, original air date April 1, 1962, season 3 #93.
The clothing the Cartwrights wore every week were pretty authentic for the time period and status of the family. Although it was understood that the Cartwrights were wealthy, they ran a working ranch where every member worked very hard just as their hired men did.