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Colin Mudford: A 12-year-old Australian boy determined to convince a cancer expert to treat his younger brother. He is sent by his parents to stay with his relatives in London during the family's difficult times.

Alistair: Colin's shy English cousin. While Colin is in London, Alistair becomes involved with Colin's ambitious schemes to find a cure for Luke's cancer.

Aunty Iris: Colin's aunt (his mother's sister) and Alistair's overbearing mother. She is friendly towards Colin but is frightened by the fact that he is so open about Luke's cancer.

Uncle Bob: Colin's uncle, Aunt Iris's husband and Alistair's overbearing father. Bob is stingy with money, critical of the Royal Family and is a fan of the DIY hardware house.

Ted: A Welsh man living in London. He is an unemployed gay man because he is taking care of his dying boyfriend.

Griff: Ted's partner, who discovered that he had developed AIDS shortly after moving to London. Colin visits Griff in the hospital and reunites him with Ted.

Mrs. Mudford: Colin and Luke's mother. She is distraught over the diagnosis of her younger son and sends Colin to London to stay at her sister's house.

Mr. Mudford: Colin and Luke's father. He travels to Sydney where Luke is diagnosed with cancer, prompting him to send Colin to England.

Luke Mudford: Colin's younger brother, diagnosed with terminal cancer after collapsing in his living room. Colin attempts to find a cure for him.

Dr. Graham: Considered the world's leading expert on cancer. Ted informs her of Colin's situation and she calls up Luke's doctors in Sydney, only to find out bad news.

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