The mule would be considered postzygotic. This is because of the usually sterile reproductive traits that are commonly associated with being a hybrid.
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a postzygotic barrier
A saddle mule is a mule used for transportation or riding, were as a pack mule is a mule used solely for transporting luggage rather then people.
Mule Skinner
Mules are sterile, a mule is the offspring of a donkey and horse, therefore sterile. A male mule can mate with a female mule, but will never get her pregnant.
A male mule is always sterile, however , rarely, a female mule will be able to reproduce.