You will only ever capitalize sir when it is a title.
Example:
Sir Elton John
You will only ma'am when it is the beginning of a sentence (it is never a title).
Example:
Ma'am, you are dismissed!
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You capitalize "Sir" and "Ma'am" when they are used as a direct address, such as "Yes, Sir" or "Thank you, Ma'am." In other contexts, like when referring to a person in third person, you do not capitalize them, as in "the sir at the counter."
Just the S
Capitalize the first word in a sentence. Capitalize proper nouns, such as the names of people and places. Capitalize the pronoun "I." Capitalize the first word of a quote. Capitalize days of the week, months, and holidays. Capitalize the titles of books, movies, and songs. Capitalize the first, last, and important words in titles.
In "Yours truly," you capitalize the first letter of each word if you are using it as a complimentary close in a letter, as it is a formal sign-off.
No, you do not capitalize the second word in the complimentary closing.
It is not necessary to capitalize pronouns in titles unless they are at the beginning of the title.