You would capitalize "science" only if it is the first word in the sentence.
Examples:
Science is my niece's favorite subject.
Ralph was always quick to answer, with answers not based in science.
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In general, you do not capitalize "math" and "science" in a sentence unless they are used as part of a title or at the beginning of a sentence.
Only if it's at the beginning of a sentence.
Example: Science is the general understanding of things around us.
The word "math" is typically not capitalized unless it is at the beginning of a sentence or part of a title where capitalization rules apply.
Typically, you capitalize the word "Science" when referring to it as a proper noun or when it is the first word in a sentence. For example, "Science has made significant advancements in recent years."
You do not capitalize science fiction. If you look any word up in the dictionary, you will learn if it should be capitalized. The rule: Capitalize names of courses: Economics, Biology 101. (However, we would write: "I'm taking courses in biology and science fiction this summer.")
Yes, you should capitalize "Computer Science" as it is the name of a specific field of study.
In general, you do not need to capitalize class subjects unless they are proper nouns or the first word of a sentence. For example, you would capitalize "English" but not "mathematics" in a paragraph.