Tun Dr. Mahathir's granddaughter is named Shaista Mayada Sosrowardoyo
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Step-great-granddaughter
If you really need a relationship term, use granddaughter-in-law. Most people would merely say "my grandson's wife."
Your grandfather's brother is your great uncle. Your great uncle's daughter's daughter (his granddaughter) is your second cousin.
Your brother's granddaughter is your great niece and you are her great uncle if you are a man, or her great aunt if you are a woman..
Your sister's granddaughter is your great niece and you are her great aunt (if you are a woman) or great uncle (if you are a man).