Disease killed millions of Native Americans
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The Columbian Exchange was a biological and cultural exchange of plants (especially potato, maize and various fruits), animals (e.g. horses), humans (via slavery) and their culture and ideas, and communicable diseases between the Old World and the Americas after Christopher Columbus's first voyage to the Caribbean in 1492.
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Labour Exchange, UK spelling, means Job Centre nowadays but it's origins lie in Victorian times and the Workhouses. The exchange being that you exchanged your labour for a roof over your head and food.
Drachmai. The drachma was the unit of currency. They would have exchanged it for clothes, food, or anything else that was for sale.
Some slaves came with their owners when they were settlers. Others came [were actually shipped] from the Colombian Exchange. Others that were legal settlers became slaves because of their race.