Spoiled beef
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Disease
The Spaniards' weapons were much more powerful and durable,making it easy to kill.The Aztecs also had diseases spreading, which killed many of them.
There is a controversy over how Moctezuma Xocoyotzin actually died, but the argument basically is that the Spaniards from back then say that the Aztec people killed him in a revolt of the government with rocks and the descendents of the Aztec people say that the Spaniards killed Moctezuma once they realized he had no more power over his people.
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Begun to make laws against it and send over more soldiers