According to Collins Dictionary, cousin : uncle :: second cousin : second uncle. The father of your cousin is your uncle, so the father of your second cousin is your second uncle. It is a way to remove some of the ambiguity of the "first cousin once removed" relationship. This term is used all over the world and is slowly gaining acceptance in the US due to its ability to distinguish the generation of each person.
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Only if his uncle is a 1st. If his uncle is a 2nd, then your son is a 3rd. If his uncle is still living, then your son can also be a "Jr."
Your grandfather's brother is your great uncle. Your great uncle's daughter's daughter (his granddaughter) is your second cousin.
Your great uncle's granddaughter is your second cousin.
The brother of your aunt's husband is not your uncle. Also the brother of your uncle who is not your uncle is your father.
Assuming we are talking direct line, your uncle is a sibling to one of your parents. His uncle is also an uncle to one of your parents and therefore your grand uncle.