It's a long standing prejudice. Partially propagated by the Catholic church, there had been various pogroms against the Jews through out the medieval period. They were blamed for the black death (by poisoning wells) and various atrocities were carried out such as the attack in York where 200 were burnt to death in a tower. Also one of the targets of the Inquisition were the Jews. The Nazi's just used existing prejudice and forged medieval documents to justify their actions.
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The Nazis blamed (scapegoated) the Jews, accusing them of:
In other words, the Nazis demonized the Jews.
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By the time of the Holocaust Hitler no longer needed a scapegoat. It was during the political campains that Hitler used scapegoats. Yes they were the only ones as what he said about the socialists was arguably true.
Because in World War 2, Germans used them as Scapegoats, blaming everything on them.
Jews were the largest victims of the Holocaust with 7 out of 10 Jews in Europe being murdered during the holocaust. Jews were discriminated against because they were not considered racially pure or part of the Aryan Race (ideally blonde haired blue eyes). And Hitler used propaganda against the Jews blaming the whole of world war one on the Jews, this brainwashed Nazis.
Jews have been used as scapegoats for centuries because they didn't have a country or a whole area which is for Jews. Hitler blamed the Jews for everything which is bad for Germany. This is called Antisemitism
The nazis used jews and poles and homosexuals and disabled people as scapegoats because they considered these group of people unfit to be on the face of earth and viewed them as weakening the gene pool of the Germans.