Acetylcholine
a neurotransmitter
Neurotransmitters are stored in synaptic vesicles in the terminal bouton of pre-synaptic axons. They are released from the terminal bouton into the synaptic cleft and the neurotransmitters exert their action on the post-synaptic neurons.
Synaptic vesicles in the neuromuscular junction contain acetylcholine (ACh) which is the neurotransmitter for initiating muscular contractions.
Acetylcholine is NOT the only chemical transmitter released by nerve endings. There are literally dozens. Ach is only the first discovered. Others include: glutamate, aspartate, serine, gamma-aminobutyric acid, glycine,dopamine, norepinephrine, epinephrine (adrenaline), histamine, serotonin, melatonin, adenosine, anandamide, True ACh was discovered first and is not the only neurotransmitter released, BUT Acetylcholine is basically the one of most important in producing an impulse.
Vesicles containing the neurotransmitters are caused to fuse with the neuron's cell membrane, which thereby presents the neurotransmitters to the outside of the neuron, into the synapse.As I'm sure you know a neurotransmitter is how two neurons communicate at a synapse. It can be one of many molecules, often nor-epinephrine/nor-adrenaline. Neurotransmitters are stored in structures called vesicles in a bulb at the end of the axon the presynaptic neuron. These vesicles are like balloons containing the neurotransmitters, what would be the rubber of the balloon is actually made of the same plasma membrane that surrounds the rest of the cell. When the Action Potential (AP) coming down the axon gets to the bulb it causes Ca ion channels to open. These channels are membrane bound proteins ant act as voltage gated channels in the same way the Sodium ion channels in the axon do. The opening of these channels allows calcium entry into the cells. There are another class of membrane bound proteins that are important here, the Docking proteins. Ca ions activate the docking proteins by binding to them. What these proteins do is effectively grab the vesicles, containing the neurotransmitter, and make the membrane merge with the cells membrane. This is exactly like the opposite of phagocytosis, the cell then secretes the neurotransmitter into the synaptic cleft.The neurotransmitter must then & isreleased from the receptor site, in order to prevent continuing and constant over-stimulation of the post-synaptic neuron. It can be carried back to the presynaptic neuron for either repackaging into vesicles or broken down there by enzymes, or some neuropeptide neurotransmitters simply diffuse away into the surrounding medium, and one (acetylcholine) is broken down right in the synaptic cleft.
Yes, it does. In contrast, the sympathetic nerves release adrenaline
ACh is produced at the intercellular level and is stored in vesicles at nerve endings. nerve endings release ACh ACh attavhes to the receptor site at the receiving nerve ACh is broken down by AChE to prevent accumulation
Botulinum toxin latches onto specific proteins in nerve endings and irreversibly destroys them. These proteins control the release of acetylcholine, a neurotransmitter that stimulates muscle cells.
False. Nodes of Ranvier are sections along a mylenated axon that are not mylenated. Instead they contain numerous voltage gated Na and K channels. These channels help transmit the chemical depolarization along the axon until it reaches the synaptic node. Neurotransmitters are stored in synaptic vessicles in the synpatic node.
Endings are added to roots. These endings are called suffixes by the way.
How many wed endings are there?
Alternate Endings was created in 2004.