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Primarily because they may cause phlebitis or tissue necrosis if given undiluted. This may be because of the acidity/alkalinity of the product, or the high osmolarity of the solution. One common example is an anti-nausea medication called Phenergan, which often causes pain if given undiluted and has even caused loss of fingers due to necrosis and tissue destruction.

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Q: Why some intravenous medications need to dilute before administering?
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Crystalloids are commonly used in medicine for fluid resuscitation, replacement, and maintenance in patients who require intravenous hydration. They are used to treat dehydration, maintain electrolyte balance, and support blood pressure in various clinical settings such as surgery, trauma, and critical care. Crystalloids are also used to dilute medications for intravenous administration.


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distillation it is method which is used to seprate diffrent chemical substance on the basis of thier volatilities.


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The butter was too rough, so I had to mix it with water to dilute it and keep cooking.To make a sauce, dilute gravy by adding milk and heat.Ammonia can be used for any cleaning job if you dilute it with water.


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Medications that may affect a uric acid urine test include diuretics, aspirin, and vitamin C supplements. Diuretics can increase urine volume and dilute uric acid levels, while aspirin and vitamin C can interfere with uric acid measurements in urine. It's important to inform your healthcare provider about any medications you are taking before a uric acid urine test.


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