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1. Fast onset of action
Effervescent tablets have major advantage that the drug product is already in solution at the time it is consumed. Thus, the absorption is faster and more complete than with conventional tablet. This is particularly helpful in treating acute symptoms of pain. Faster absorption means faster onset of action, critical in treating acute symptoms such as pain. Buffered preparations with adjustable stomach pH optimize formula performance characteristics.
Effervescent drugs are delivered to the stomach at a pH that is just right for absorption. Many medications travel slowly through the gastrointestinal tract or have absorption that is hampered by food or other drugs. To achieve desired absorption levels, such drugs have to be often administered as injections or with increased dosages.
2. No need to swallow tablets
Effervescent medications are administered in liquid form so they are easy to take as compared to tablets or capsules. The number of people who cannot swallow tablets or who dislike swallowing tablets and capsules is growing. Many diseased conditions require the patient or customer to swallow several tablets at a time. The elderly, in particular, have difficulty in swallowing tablets. With an effervescent dosage form, one dose can usually be delivered in just 3 or 4 ounces of water. The amount used when someone swallows a conventional tablet or capsule.
3. Good stomach and intestinal tolerance
Effervescent tablets dissolve fully in a buffered solution. Reduced localized contact in the upper gastrointestinal tract leads to less irritation and greater tolerability. Buffering also prevents gastric acids from interacting with the drugs themselves, which can be a major cause of stomach and esophageal upsets.
4. More portability
Effervescent tablets are more easily transported than liquid medication because no water is added until it's ready to use.
5. Improved palatability
Drugs delivered with the effervescent base, taste better than most liquids, mixtures and suspensions. Superior taste masking is achieved by limiting objectionable characteristics and complementing formulations with flavors and fragrances. Effervescent pharmaceuticals retain their flavor after lengthy storage. The effervescent tablets essentially include flavorings so they taste much better than a mixture of a non-effervescent powder in water. Moreover, they produce fizzy tablets, which may have better consumer appeal than the traditional dosage forms.
6. Superior stability
Excellent stability is inherent with effervescent formulations, particularly surpassing liquid forms.
7. More consistent response
Drugs delivered using effervescent technology have predictable and reproducible pharmacokinetic profiles that are much more consistent than tablets or capsules.
8. Incorporation of large amounts of active ingredients
In many cases, one effervescent tablet will equal to three conventional tablets in active dose amounts.
9. Accurate dosing
Researchers have shown that effervescent tablets enhance the absorption of a number of active ingredients (e.g. disulfiram and caffeine), compared to conventional formulations. This is because the carbon dioxide created by the effervescent reaction can induce enhanced active-ingredient permeability due to an alteration of the paracellular pathway. The paracellular pathway is the primary route of absorption for hydrophilic active ingredients in which the solutes diffuse into the intercellular space between epithelial cells. It is postulated that the carbon dioxide widens the intercellular space between cells, which leads to greater absorption of active ingredients (both hydrophobic and hydrophilic). The increased absorption of hydrophobic active ingredients could be due to the non-polar carbon dioxide gas molecules partition into the cell membrane, thus creating an increased hydrophobic environment, which would allow the hydrophobic active ingredients to be absorbed.
10. Improved therapeutic effect
The effervescent components aid in improving the therapeutic profiles of the active ingredients. They also help in solubilization of poorly soluble drugs.
maintains suitable pH for better absorption.
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Which antibiotic drug usefull in effervescent tablet?
Amoxicillin is useful in effervescent tablet form.
How do you put effervescent in a sentence?
She dropped an effervescent tablet into a glass of water, causing it to fizz and dissolve rapidly.
Which gas there in effervecent tablet?
The gas in effervescent tablets is typically carbon dioxide. It is produced when the tablet is dissolved in water and reacts with bicarbonate or carbonate ingredients in the tablet.
What are the ingredients of the effervescent tablet?
sodium bicarbonate, citric acid,sodium benzoate and water soluble flavour
How do make effervescent tablets?
Effervescent tablets are typically made by blending active ingredients with granulation agents and effervescent ingredients like citric acid and sodium bicarbonate. The mixture is then compressed into tablet form. Finally, the tablets are coated to prevent them from reacting with moisture in the air.
What could be a sentence with the word effervesce in it?
You are a very effervescent person. Better: She has a lively, bubbly, effervescent personality. effervescent - bubbly, fizzy Coke is an effervescent drink.
What is the chemical reaction if you made an effervescent milk tablets that combine skimmed milk citric acid natrium bicarbonate?
When the effervescent milk tablet dissolves in water, the citric acid reacts with sodium bicarbonate to produce carbon dioxide gas. This gas creates the fizzing or bubbling effect commonly seen in effervescent tablets, helping to dissolve the tablet and release the skimmed milk components into the solution for consumption.
What will happen when you drop an effervescent tablet to 56 degree water?
When you drop an effervescent tablet into 56 degree water, the tablet will start to fizz and dissolve rapidly. The effervescence is caused by a chemical reaction between the ingredients in the tablet (such as citric acid and baking soda) and the water, which releases carbon dioxide gas bubbles. As a result, the tablet will dissolve, releasing any active ingredients it contains into the water.
What is stability requirement for Effervescent tablets?
Effervescent tablets should be stored in a cool, dry place to prevent exposure to moisture. They should also be stored in airtight packaging to prevent them from reacting with ambient humidity and losing their effervescent properties. Additionally, they should be protected from light and excessive heat to maintain their stability.
What is a noun for effervescent?
The noun form for the adjective effervescent is effervescence.
What is the chemical formula of effervescent tablet?
Effervescent tablets usually contain a combination of various substances like citric acid and sodium bicarbonate, along with other ingredients like flavorings and binders. The chemical formula may vary depending on the specific ingredients used in the tablet.
What evidence of a chemical reaction might you see dropping an alka-seltzer tablet into a glass of water?
You might observe fizzing or bubbling as the tablet dissolves in the water due to the release of carbon dioxide gas. This effervescent reaction is evidence of a chemical reaction occurring between the ingredients in the tablet and water.
