Atropine does not only block nicotinic receptors but also acetylcholine at muscarinic receptors
The muscarinic receptors in the vasculature are not inneravated by the parasympathetic nervous system. Therefore, atropine binds to these receptors, but causes no response since it is a pure muscarinic antagonist.
Atropine
it affects the receptors
The parietal cell in the stomach secrets gastric acid, which is hydrochloric acid (HCl). The Secretion of HCl by the parietal cell is stimulated by receptors for acetylcholine (muscarinic), histamine, and gastrin. The enterochromaffin cells (ECL) also have gastrin receptors and muscarinic receptors. ECL cells release histamine which reacts with H2 receptors (histamine 2 receptors) on parietal cells. Somatostatin is released by delta cells and decreases histamine release by ECL cells.
Histamine receptors in the stomach control acid production, and blocking them reduces acidity. The H2 receptors in the stomach are treated with different agents than the H1 receptors in the brain, there is little overlap.
Atropine counteracts nerve gas by blocking the action of acetylcholine at nerve receptors. Nerve gases inhibit the enzyme acetylcholinesterase, which leads to an accumulation of acetylcholine and overstimulation of nerve cells. Atropine acts as an antidote by binding to the same receptors as acetylcholine, preventing excessive stimulation.
Histamine is the endogenous substance that causes bronchoconstriction by binding to histamine receptors on smooth muscle cells in the airways, leading to their contraction and narrowing of the airways.
yes
Ranitidine (Zantac) is an H2 blocker. Histamine is released by nerves to the stomach and bind to H2 receptors to signal the stomach to make acid. Ranitidine blocks this interactions and so decreases acid production. The drugs called "antihistamines" block the H1 histamine receptors so that histamine (the same chemical) released by immune cells can't interact with other immune cells to cause allergies.
Yes, atropine is known to dry bronchial secretions by blocking the effects of acetylcholine on muscarinic receptors in the respiratory system, leading to decreased mucus production.
http://www.pharmacorama.com/en/Sections/Acetylcholine_2_2.php#5Acetylcholine is a bronchoconstrictor.