Mescaline, an alkaloidal halluncinogen, is one of the active ingredients in the buttons harvested from the Peyote cactus, indigenous to the American Southerwest desert. This hallucinogen has been used for centuries in religious rituals by various Native American tribes. It seems to have made its way into the illicit recreational drug market in the early 1960's. Like so many hallucinogens, it isn't a very popular drug, as this type of drug doesn't really make you feel good, relaxed, optimistic, happy, etc. Instead, it tends to amplify the mood you're already in. Also, alkaloidal compounds, especially ones harvested from a natural source, have a tendency to cause gastritis and vomiting -- never a good time. Today, the majority of mescaline users -- I think -- are still Native Americans using it legally as part of religious ceremonies. Those that take it recreationally typically do so for the near-hallucinations it produces and the somatic effects.
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