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Usually, the vehicle used for a intramuscular drug contains oil or a "fatty liquid". The amount of liquid injected is generally bigger in an IM injection and the drug might also be more irritative. The nail used is generally bigger and longer.
For these reasons, almost all IM injections are more painful than SC injections.
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Earn +20 ptsQ: Why are intramuscular injections more painful than subcutaneous injections?
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