Why are binders added in solid dosage forms of drugs?

Answer 1

Binders are added in wet or dry form to cohesively hold the active pharmaceutical ingredient together with other inactive ingredients. To increase their effectiveness, they can be added as a solution.

Answer 2

Binders are added to drugs cohesively hold the active pharmaceutical ingredient together with the inactive ingridients. The hard granules formed will flow well and should not crumble.

Two types of binders are used: wet binders and dry binders. Wet binders are used in wet granulation. Examples include sucrose, dextrose, starch paste, polyvinypyrrolidone, and solvents such as water or acetone. On the other hand, dry binders such as microcrystalline cellulose are used in dry granulation.