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HLA is codominantly expressed because this gives the greatest variety and therefore the biggest chance MHC will have to bind to a peptide.
MHC class 1 can bind up to 10 peptides and it is anchored 4x which makes it much more strict in terms of ability to the range it can bind compared to MHC class 2 which can bind up to 50 peptides and only anchors 2x.
e.g. If you only had your mothers HLA-A, your MHC wouldn't be able to identify whatever peptides that specific HLA-A (mom's) had the ability to bind to.
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How many classes are there of HLA gene products?
There are three classes of HLA gene products: Class I (HLA-A, HLA-B, HLA-C), Class II (HLA-DP, HLA-DQ, HLA-DR), and Class III (complement proteins). These gene products play a crucial role in the immune system by presenting antigens to T cells and regulating immune responses.
When was Tha Hla born?
Tha Hla was born in 1916.
What does HLA stand for in HLA gene family?
HLA in the HLA gene family stands for Human Leukocyte Antigen. The genes are responsible for producing antigens in the body to fight viruses and bacteria.
When did James Hla Kyaw die?
James Hla Kyaw died in 1919.
When did Sanda Min Hla die?
Sanda Min Hla died in 1363.
When was Hla Tun born?
Hla Tun was born on 1951-07-11.
When was Hla Min born?
Hla Min was born on 1958-01-26.
When did Hla Pe die?
Hla Pe died on 2007-07-31.
When did Hla Thaung die?
Hla Thaung died on 1949-04-28.
When was James Hla Kyaw born?
James Hla Kyaw was born in 1866.
When was Saw Mon Hla born?
Saw Mon Hla was born in 104#.
When was Hla Pe born?
Hla Pe was born on 1913-01-08.
