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HLA is codominantly expressed because this gives the greatest variety and therefore the biggest chance MHC will have to bind to a peptide.
MHC class 1 can bind up to 10 peptides and it is anchored 4x which makes it much more strict in terms of ability to the range it can bind compared to MHC class 2 which can bind up to 50 peptides and only anchors 2x.
e.g. If you only had your mothers HLA-A, your MHC wouldn't be able to identify whatever peptides that specific HLA-A (mom's) had the ability to bind to.
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Class you MHC genes code for?
Class 1 = HLA-A, HLA-B, and HLA-CClass 2 = HLA-DP, HLA-DQ, and HLA-DR
Why is hla called an antigen?
What is HLA and HLA typing?
When was Tha Hla born?
Tha Hla was born in 1916.
What does HLA stand for in HLA gene family?
HLA in the HLA gene family stands for Human Leukocyte Antigen. The genes are responsible for producing antigens in the body to fight viruses and bacteria.
Is HLA only found on leukocytes?
HLA (human leukocyte antigen) is the name for the MHC (major histocompatibility complex) found in humans. MHC class I molecules (HLA-A, HLA-B, HLA-C) are found on pretty much all cells (some important exceptions are red blood cells). MHC Class II molecules (HLA-DQ, HLA-DP, HLA-DR) are found on special antigen presenting cells, which include B-lymphocytes, dentritic cells, and macrophages.
When did Sanda Min Hla die?
Sanda Min Hla died in 1363.
When was Hla Tun born?
Hla Tun was born on 1951-07-11.
When was Hla Min born?
Hla Min was born on 1958-01-26.
When did Hla Pe die?
Hla Pe died on 2007-07-31.
When did Hla Thaung die?
Hla Thaung died on 1949-04-28.
When was James Hla Kyaw born?
James Hla Kyaw was born in 1866.
When did James Hla Kyaw die?
James Hla Kyaw died in 1919.
