Amphetamines were first introduced in the 1930s as a remedy for nasal congestion, and marketed over-thecounter as an inhaler named Benzedrine. These drugs were also used medically to treat obesity and depression. Different types of amphetamines were available from the 1930s until the 1970s. People eventually found, however, that the medical value of amphetamines is offset by their dangerous effects and high abuse potential (the chance a drug will be abused, cause addiction or be otherwise harmful). In the 1970s, new laws restricted the medical use of these drugs. Today, only dextroamphetamine (Dexedrine®) and methylphenidate are made for medical use. All other amphetamines are made in illicit laboratories.
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The origin of Amphetamine is the plant Ma-Huang. Other origin is in laboratory. Amphetamine was first synthesized in 1887 by the Romanian chemist Lazăr Edeleanu in Berlin, Germany. He named the compound phenylisopropylamine. It was one of a series of compounds related to the plant derivative ephedrine, which had been isolated from the plant Ma-Huang (Ephedra) that same year by Nagayoshi Nagai.
Amphetamine was synthesized in a laboratory. It is in the same class of chemicals as ephedrine, which is derived from a plant.
Methamphetamine is synthesized from ephedrine.
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