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At every junction between a motor neuron and skeletal muscle fibers
Wiki User
∙ 11y ago
Wiki User
∙ 14y agoIn the Synaptic Cleft.
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What statement describes nicotinic acetylcholine ACh receptors as opposed to muscarinic ACh receptors?
Nicotinic receptors are closed until ACh molecules bind to the receptor proteins.
How does the incapacitating agent 3-quinuclidinyl benzilate affect the human body?
Competes with ACh at the nerve receptors and results in under stimulatin of the receptors.
How does the incapacitating agent 3-quinuclindinyl benzilate affect the human body?
Competes with ACh at the nerve receptors and results in under stimulatin of the receptors
How is neostigmine chemically used to treat myasthenia gravis?
Neostigmine is a competitive irreversible inhibitor of Acetylcholinesterase (AChE), an enzyme responsible for breaking down acetylcholine (ACh). Myasthenia gravis is caused by the body producing too little ACh receptors. As stimulating the ACh receptors is needed for nervous transmission, the nerve signals cannot be transmitted causing muscle weakness and fatigue. Neostigmine is hence used to inhibit AChE so that less ACh gets broken down. This leads to more ACh binding to the ACh receptors causing muscular contraction.
What does ach do at a neuromuscular junction?
ACh (acetylcholine) binds to receptors at the NMJ (neuromuscular junction) to induce contraction of muscle.
What is ACh receptors?
ACH receptors can be defined as an integral membrane protein that responds to the binding of acetylcholine, a neuoyansmitter. Two example are nicotinic acetyl line receptors and muscarinic acetylcholine receptors. .
What neurotransmitter is found at the synapse between nerves and human skeletal muscle cells?
Acetylcholine is the neurotransmitter at the neuromuscular junction.
The first thing that stops a contraction after the nerve stops sending ACh?
AChE destroys the ACh and they are removed from the membrane receptors.
What enzyme removes ACh from receptors so stimulation of muscle cells cease?
ACh esterase, which breaks ACh down into an acetyl group and a choline group. This is then taken up by the neurone and some is reformed into ACh.
What is m-cholinomimetics?
they stimulate the action of ACh at post ganglionic muscarinic receptors.
Why does atropine effect histamine receptors?
It doesn't atropine only acts on muscarinic receptors (it's a competitive antagonist here for ACh), but histamine acts on different receptors (histamine receptors). There is no direct interaction between atropine and histamine receptors
A deficiency of ACh receptors in a motor end plate would cause and is called?
myasthenia gravis
