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I'm not an expert:
It would seem to me; however, that the time of day Chantix is taken would have minimal effect on its metabolism or the levels of varenicline in the bloodstream. What would have such an effect on the levels of varenicline in the bloodstream would be taking at a different time each or any day. Suggest that the prospective non-smoker pick a time of day to take it and use that time of day consistently throughout the course of administration of the drug. Generally it is not recommended that does be "made up." If you miss a dose - skip it and get back on schedule.
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