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Q: What time is best to take gliclazide?
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Can you take gliclazide and metformin together?

Yes, both drugs can be taken together. However, gliclazide might increase metformine's effectiveness. Make sure you check blood glucose more often at the beggining of both treatment.


Chemical synthesis of oral hypoglycemic agent gliclazide?

It is two step chemical process. In a first step p-toluene-sulphonamide is reacted with methyl chloroformate to yield carbamate intermediate which is in the second step in a condensation reaction with N-amino-3-azabicyclo (3,3,0) Octane hydrochloride converted to crude gliclazide. After crystallization from methanol pharmaceutically pure gliclazide is obtained.


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