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Lithium is often used to treat Bipolar depression as it lowers the levels of noradrenaline, anti depressants such as SSRI's: Selective Serotonin Reuptake Inhibitors or NARI's: Noradrenaline Reuptake Inhibitors, can be used to treat Unipolar/Manic depression as they raise the levels of Noradrenaline and Serotonin.

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