A feature of ketosis is?
Ketosis is the state of having elevated ketone bodies in the
blood stream. Ketone bodies are formed by ketogenesis when liver
glycogen stores are depleted. Ketone bodies are acidic, and
prolonged exposure can overrun the compensatory mechanisms
resulting in ketoacidosis ( pH under 7.35).
Most commonly, ketoacidosis is diabetic ketoacidosis (DKA),
resulting from increased fat metabolism due to a shortage of
insulin. It is associated primarily with type I diabetes, and may
result in a diabetic coma if left untreated.
In alcoholic ketoacidosis, alcohol causes dehydration and blocks
the first step of gluconeogenesis. The body is unable to synthesize
enough glucose to meet its needs, thus creating an energy crisis
resulting in fatty acid metabolism, and ketone body formation.