The Importance of Drug receptor is when we add Drug + Receptor we form this Pharmaceutical - Response which causes the drug to stay or metabolize in a finite or fix period of time which causes to avoid or lower the adverse effect of the drug.
DRUG + RECEPTOR > DRUG - RECEPTOR COMPLEX
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PHARMA RESPONSE
An agonist stimulates the receptor, whereas an antagonist blocks a receptor.
A receptor.
The only way to change the pA2 would be to alter the nature of the receptor, because the pA2 is essentially a measurement of the affinity of the antagonist drug for the receptor. So, in order to change this value, one would need to change the receptor in a way that changes the binding affinity of the drug.
Receptor Site Theory
Heroin
Hase not specific receptor
Drug having defenite affinity to bind the receptor but, does not activate it (no intracelluler changes occur after drug receptor complex is formed), thus the receptor in other word is being blocked, and the the respective pharmacological response which was supposed to be occured by the binding of the agonist, does not occur.
Bronchodlator.
A pesudoreceptor is a molecular binding pocket, and is one of the key structures in improving drug screening. This is made possible by a combination of ligand matching and receptor mapping which allows an entrance for the modeling that drug-screening projects require.
An agonist binds to a receptor and stimulates it (turns it on). An antagonist binds to a receptor and blocks it from being activated by other molecules (turns it off).
Angiotensin ll receptor antagonist
Atropine is generally considered to be a cholinergic muscarinic receptor antagonist.