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What is the difference with metformin hydrochloride mr tablets 1gram to taking 500g of the normal metformin tablets?
Wiki User
∙ 13y ago
The 'MR' in the title of the 1 gram/1000mg capsule means modified release, i.e. the drug disperses slowly over time to release the active ingredient gradually through the day.
The 500mg separate dosage tablets are immediate release, and the drug enters your bloodstream within minutes of taking each dose, so there are peaks and troughs of concentration of the drug in your blood.
Obviously, having a slow release and the drug being introduced into your bloodstream throughout the day is a better way to manage your blood sugar/Diabetes, as well as less invasive to your stomach.
Wiki User
∙ 13y ago
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