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Heparin is an indirect antithrombotic agent. When antithrombin III binds to thrombin, the thrombin gets broken down. However, this binding reaction happens at a very slow rate. Heparin can sped up this reaction by inducing a confrontational change in antithrombin III.

Warfarin is a vitamin K epoxide reductase inhibitor. It prevents vitamin K from being reduced. Vitamin K is an essential cofactor for gamma-glutamyl carboxylase. This enzyme turns the Glu of Factor X into Gla. The calcium ions can only bind to Gla to enable Factor X to undergo a confrontational change so that it can itneract with the tissue factor and the VIIa cofactor.

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6y ago
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6y ago

Dipyridamol inhibits PDE and nucleoside transporters. This enhances the activity of cAMP . This results in the intracellular calcium being decrease and GPIIb/IIIa being blocked and platelet aggregation can hence be inhibited.

Clopidogrel acts on the ADP receptors. It prevents P2Y12 from being formed and hence also prevents GPIIb/IIIa from being formed. It can therefore reduce platelet aggregation.

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Q: What is the difference between the mechanisms of action of heparin and warfarin in treating thrombosis?
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What fights thrombosis?

The most frequently used is warfarin. The class of these chemicals is called anticoagulants.


What chemical fights thrombosis?

The most frequently used is warfarin. The class of these chemicals is called anticoagulants.


Does warfarin dissolve a blood clot?

Yes it does and it also thins blood which is why it is used in the case of stroke heart attack ant thrombosis.


What is aspirin or warfarin used for in treating atrial fibrillation and flutter?

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There is no difference; they are the same drug.


What is the treatment for deep vein thrombosis?

Thrombolytic Doctors will put you on some kind of anti coagulation therapy to prevent more clotting. Usually a brief course of heparin then warfarin.


What is treatment for deep vein thrombosis..?

Thrombolytic Doctors will put you on some kind of anti coagulation therapy to prevent more clotting. Usually a brief course of heparin then warfarin.


What warfarin number is better 2.1 or2.9?

I suppose that this difference is not so important.


Can you stop taking warfrin?

You should not stop taking warfarin except on your doctor's recommendation as your blood will become more likely to clot potentially leading to serious health problems such as pulmonary embolism and deep vein thrombosis.


What is the most likely adverse event that could result from switching an infant with congenital heart disease who is taking warfarin from breast milk to formula?

Warfarin works by slowing the blood clotting process down. It prevents the clotting proteins( vitamin K) from doing their job fully. Babies on formula may require higher doses of Warfarin because there is less vitamin K in formula than there is in breast milk. So, the most likely adverse event would be thrombosis since there won't be adequate level of Warfarin in the blood if the dose is not adjusted.


What is pulminory Thrombosis and how is it treated?

Pulmonary thrombosis is when a blood clot from another part of the body (usually the deep veins of the leg) dislodges from the place of origin and settles somewhere in the lungs. This blocks blood flow into the lungs. It is treated by a clot buster in the short term to bust the clot and if it is a chronic problem they are given Warfarin or something similar to prevent future clots


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