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Azithromycin (the generic of Zithromax) is better than erythromycin due to being taken less often, having less GI side effects and a broader range of coverage (it kills more).

It is superior to both erythromycin and clarithromycin (Biaxin) because it causes fewer drug interactions.

Some doctors like clarithromycin better than azithromycin for things like sinus infections because they think it gets to the site of infection better.

Erythromycin has other uses and is much less expensive than the other two.

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Q: What is the advantage of Zithromax over other macrolides?
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