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What is norfluoxetine?

Updated: 4/27/2022
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14y ago

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I also have this question. On reading through the literature I have gathered that norfluoxetine is the demethylated form of fluoxtine and the reactive metabolite. From what I can gather, you take fluoxetine into your body, and it has a methyl (CH3) group cleaved from the amino group to yield norfluoxetine:

http://pages.cs.wisc.edu/~caitlin/papers/Prozac/


However, also listed is fluoxetine HCl, which i assume is the actual form fluoxetine is produced in pharmaceutically, with the HCl stabilizing the amino group of fluoxetine.

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14y ago
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