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What is neurotoxins?

Updated: 4/28/2022
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15y ago

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Neurotoxins are substances that affect the nervous system of animals, insects, etc, usually resulting in partial paralysis or death, depending on the substance itself.

Although they can be man-made, most neurotoxins are found in nature, and humans have simply improved on nature's lethality. The most common examples of NT's in nature are the venom used by Spiders, snakes, etc. When spiders attack a prey, the insect or animal is instantly paralyzed, and the toxin begins to dissolve the area around the sting or bite area. They literally dissolve the flesh around the bite area while the victim is paralyzed. Some spider venom will literally hollow out an insect victim from the inside out to where there's nothing left but the outer shell.

There are many spiders whose venom is toxic enough to kill humans. Other animals secreting such types of venom are some types of jellyfish, frogs, certain fish, etc. While the majority of them are only lethal to animals and insects within their own world, a few have venom strong enough to kill or severely injure people.

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6y ago

A neurotoxin is really a poison (toxin) that affects the nervous system, especially the neurons.

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How does neurotoxins work in the human body?

Neurotoxins disrupt the nerve signalling in the human body. There are two common mechanisms by which nerve signaling is disrupted. The cell that receives the signal does so when receptors within its membrane interact with the neurotransmitters. Some neurotoxins act by blocking these receptors, making it impossible for them to receive signals. When signaling stops, nerve function is impaired or eliminated and, the neurotoxin has caused its damage.There are special enzymes in the synaptic cleft that break down certain neurotransmitters. Some neurotoxins block the actions of the hydrolytic enzymes, thereby preventing the removal of acetylcholine, leading to continuous stimulation of the neurons and, ultimately, cell death.


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