Immunosuppressive drugs, immunosuppressive agents, or immunosuppressants are drugs that inhibit or prevent activity of the immune system. They are used in immunosuppressive therapy to:
These drugs are not without side-effects and risks. Because the majority of them act non-selectively, the immune system is less able to resist infections and the spread of malignant cells. There are also other side-effects, such as hypertension, dyslipidemia, hyperglycemia, peptic ulcers, liver, and kidney injury. The immunosuppressive drugs also interact with other medicines and affect their metabolism and action. Actual or suspected immunosuppressive agents can be evaluated in terms of their effects on lymphocyte subpopulations in tissues using immunohistochemistry.[1]
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Immunosuppressant drugs greatly decrease the risks of rejection, protecting the new organ and preserving its function. These drugs act by blocking the immune system so that it is less likely to react against the transplanted organ.
used to prevent the body from rejecting a transplanted organ.immunosuppressant drugs are also used to treat such severe skin disorders as psoriasis and such other diseases as rheumatoid arthritis,Crohn's disease.and patchy hair loss (alopecia areata)
Some immunosuppressants are also used to treat a variety of autoimmune diseases:.Azathioprine (Imuran).Cyclosporin (Sandimmune, Neoral).Glatiramer acetate (Copaxone).Mycopehnolate (CellCept).Sirolimus (Rapamune)
The four main categories of immunosuppressant drugs currently used in treating patients.Cyclosporins (Neoral, Sandimmune, SangCya). Azathioprines (Imuran). Monoclonal antibodies.Such corticosteroids as prednisolone (Deltasone, Orasone)
Immunosuppressant drugs, also called anti-rejection drugs, are used to prevent the body from rejecting a transplanted organ.
Immunosuppressive-- Any agent that suppresses the immune response of an individual.
Most of the people who use immunosuppressive drugs have transplanted organs, so their bodies won't reject the new organ.