answersLogoWhite

0

Immunosuppressive drugs, immunosuppressive agents, or immunosuppressants are drugs that inhibit or prevent activity of the immune system. They are used in immunosuppressive therapy to:

  • Prevent the rejection of transplanted organs and tissues (e.g., bone marrow, heart, kidney, liver)
  • Treat autoimmune diseases or diseases that are most likely of autoimmune origin (e.g., rheumatoid arthritis, multiple sclerosis, myasthenia gravis, systemic lupus erythematosus, Crohn's disease, pemphigus, and ulcerative colitis).
  • Treat some other non-autoimmune inflammatory diseases (e.g., long term allergic Asthma control).

These drugs are not without side-effects and risks. Because the majority of them act non-selectively, the immune system is less able to resist infections and the spread of malignant cells. There are also other side-effects, such as hypertension, dyslipidemia, hyperglycemia, peptic ulcers, liver, and kidney injury. The immunosuppressive drugs also interact with other medicines and affect their metabolism and action. Actual or suspected immunosuppressive agents can be evaluated in terms of their effects on lymphocyte subpopulations in tissues using immunohistochemistry.[1]

User Avatar

Wiki User

12y ago

What else can I help you with?

Related Questions

How many mg of ondansetron do you need to get high?

Ondansetron will not give you a high. It is not that kind of medication, in the same way that you cannot get a high from an blood pressure drug or an immunosuppressive drug.


What are the drug interactions associated with taking the Thunder God vine?

People taking immunosuppressive drugs such as prednisone should not use thunder god vine.


What can be done to reduce the risk of organ rejection?

To prevent the patient from rejecting the donated organ, usually the drug Tacrolimus will be used to immunosuppress the patient. (Although sometimes it's Sirolimus). Steroids are also commonly used alongside the main immunosuppressant.


Is Trichoderma used as a drug in Organ Transplant?

I don't believe so - you are correct in thinking that the first immunosuppressive (Ciclosporin) was derived from a fungus, however that fungus was "Tolypocaldium Inflatum", which as far as I am aware is not related to Trichoderma.Tacrolimus (a more recently developed immunosuppressive) is derived from the bacteria Streptomyces tsukubaensis. Other immunosuppressives ending is "imus" also come from the Streptomyces family.


Immunosuppressive drugs are given after?

organ transplantation


Why are infections a constant risk to a patient on immunosuppressive agents?

Infections are a constant risk while on immunosuppressive agents, because the immune system is supposed to prevent them.


What is a major complication of immunosuppressive therapy?

Increased risk for infection


Were immunosuppression developed in 1954?

No, the first immunosuppressive (ciclosporin) was developed in 1970's.


What kind of drug suppresses the body's immune response?

Immunosuppressant drugs are used to suppress the body's immune response. These drugs are commonly prescribed to prevent rejection of transplanted organs and to treat autoimmune diseases. They work by reducing the activity of the immune system.


Does Kidney transplantation require medication?

A regimen of immunosuppressive, or anti-rejection medication, is required after transplantation surgery


What medications are used in the treatment of systemic lupus erythematosus?

There are 4 Food and Drug Administration medications for the treatment of lupus:AspirinPrednisoneHydroxychloroquine (Plaquenil)Belimumab (Benlysta)Off label medications include prescription anti-inflammatories, rituxan (Rituxamab), cytoxan, azathioprine, methotrexate and other immunosuppressive medications.


What has the author David Timothy Shakespeare written?

David Timothy Shakespeare has written: 'Studies on the immunosuppressive action of rat seminal plasma'