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What is hemosiderin?

Updated: 4/28/2022
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Vishnumukundan

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15y ago

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A golden yellow or yellow-brown insoluble protein produced by phagocytic digestion of hematin; found in most tissues, especially in the liver, spleen, and bone marrow, in the form of granules much larger than ferritin molecules (of which they are believed to be aggregates), but with a higher content, as much as 37%, of iron; stains blue with Perl Prussian blue stain.

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Q: What is hemosiderin?
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How are terms hemoglobin hemosiderin and hemolysis related?

they are related because of blood


What is Perls test?

a test for hemosiderin, utilizing Perls Prussian blue stain.


Which of these proteins functions to store or transport iron?

ferritin, hemosiderin, and transferrin


Why hepatomegaly occurs in thalassemia?

Hepatomegaly in thalassemia occures as aresult of engorgement of hepatic paranchymal and phagocytic cells with hemosiderin deposits.


What is hemosiderin-laden macrophage?

Hemosiderin is an iron-containing pigment derived in humans from ferritin. It can be found in macrophages in small amounts throughout a number of different tissues including the bone marrow, liver and the spleen as a normal way to store iron. Under certain conditions it can pathologically accumulate in excess amounts. In hemosiderosis macrophages are hemosiderin-laden but without associated damage to surrounding tissue. When there more extensive accumulation occurs, it can lead to surrounding tissue damage, scarring and organ dysfunction. This is called hemochromatosis.


What is the chief function of hemosiderin?

Haemosiderin is a wear and tear pigment of the cells. It has no function of its on as such it colors the tissue yellow can signify ageing of the cells.


What is chief function of hemosiderin?

Haemosiderin is a wear and tear pigment of the cells. It has no function of its on as such it colors the tissue yellow can signify ageing of the cells.


Why is iron not stored or transported in its free form?

iron can not be storde or transported in its free form because is toxic. so it stored inside of cells as ferritin and hemosiderin


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How is iron stores and transported in the body?

Iron taken in excess is stored in two forms ferritin and hemosiderin. Iron that is not used for erythropoiesis is stored in the mononuclear phagocytic system (MPS) or the reticloendothelial (RE) cells of the bone marrow, liver, and spleen. The body transports iron in hemoglobin which is the substance in the red blood cells which binds to oxygen to transport to the whole body.


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