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This is an educated guess. De novo assembly means newly assembled. Imagine that a virus can be made in two fragments which have the ability to self-assemble. When the parts come together under the right conditions, they might re-assemble. If the re-assembly is correct, then the virus might be re-assembled into a fully functional virus.

With synthetic Biology, this is within the realm of reality.

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Q: What is de novo assembly of viruses?
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