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What is cellcept?

Updated: 4/28/2022
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15y ago

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Cellcept is a medication normally used in heart or liver transplant patients to prevent organ rejection. Cellcept lowers immune system response.

However, Cellcept has also recently been shown to be effective in slowing down the progression of Multiple Sclerosis. Several clinical trials are in progress combining Cellcept with the subcutaneous interferon treatment Avonex. Results are promising, and could potentially be a viable treatment for patients with Primary-Progressive MS (PPMS). Cellcept is also an off-label treatment for lupus. It is an effective immunosuppresent.

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Mycophenolate is already a generic name of the original drug Cellcept. The active ingredient is mycophenolate mofetil.


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(4E)-​6-​(4-​hydroxy-​6-​methoxy-​7-​methyl-​3-​oxo-​1,​3-​dihydro-​2-​benzofuran-​5-​yl)-​4-​methylhex-​4-​enoic acid. Courtesy of wikipedia


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Medications vary widely based on what organs are affected by the autoimmune activity. Antimalarials, prednisone and NSAIDS are used most commonly. Chemotherapies like methotrexate and cytoxan are sometimes used. Cellcept (mycophenolate mofetil) which is used to prevent organ transplant rejection is now being used for many lupus patients. New biologics are being developed which interrupt the autoimmune activity at the level of B cells. Benlysta is on its way to FDA approval and will be the first new medication developed and approved specifically for lupus since November 20, 1958.


What is the recommended usual normal Dental treatment of a patient with lupus history of stroke and kidney replacement?

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