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Beta lactamase is an enzyme, which is produced by some bacteria. This enzyme brakes the beta lactum ring that is present in beta lactum antibiotics. You have four groups in beta-lactum antibiotics. They are penicillins, cephalosporins, monobactums and carbapenems. So you naturally have the enzymes penicillinase, cephalospoinase, monobactamase and carbapenamase. Whether they are one and the same enzyme or four different enzymes is not clear to the contributor and needs comment by expert in this field.
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Why you put clavulanic acid with amoxicillin?
Clavulanic acid is an antibiotic, which selectively blocks the betalactamase enzyme. So the amoxicillin is left free to kill the bacteria, which produce betalactamase enzyme. For this advantage, clavulanic acid is added with amoxicillin.
What is an example of a penicillin mixed with a beta-lactamase inhibitor?
The drug Augmentin, for example, contains a combination of amoxicillin and a betalactamase inhibitor, clavulanic acid.
How is Ceftriaxone sulbactum combination better than ceftriaxone tazobactum?
ceftriaxone is ase third genration antibiotic and having good coverage againast gram positive and grame neative ,while sulbuctem increase its activity against betalactamase producing bcteria.
What is the specific action of co-amoxiclav?
amoxy and clav are combine together to take care bacteria who is producung an enzyme called beta lactamase. this enzyme attacks Beta lactum ring in amoxy and destroys the efficacy of Amoxy. to protect amoxy from betalactamase clavulinic acid is combine which is responsible to take care of this enzyme and ensures efficacy of amoxy .Clav in combination has no antibacterial action madhv deshpande
