Benzphetamine is category X during pregnancy. Diethylpropion is category B.
Benzphetamine is category X during pregnancy
Category A: Controlled human studies have demonstrated no fetal risk.
Drugs are all rated with pregnancy categories. Pregnancy category A- Proven safe Pregnancy category B- Not proven in humans, but widely believed to be safe and still administered. It has been proven safe in animal tests. Pregnancy category C- No safety tests have been performed, safety not known Pregnancy category D- Animal tests have shown fetal deformities, but no human tests have been done Pregnancy category X- Drug has been proven to cause birth defects in humans.
Pregnancy category is done in pharmacology. There are 5 categories. These are A, B, C, D and X. Category A means there is no possibly adverse effect of a drug on fetus. category B means there in no possible adverse effect on fetus on Laboratory Testing. category C means these is a possible adverse effect on laboratory testing animals. category D means there is a possible adverse effect on laboratory testing animals and on human fetus. And, category X means there is 95% chances of adverse effect on human fetus.
Category X: Evidence of fetal risk. Risks outweigh any benefits.
The toxicity profile of this drug when administered systemically includes granulocytopenia, anemia and thrombocytopenia. The drug is in pregnancy category C
Category C: No adequate human or animal studies; or adverse fetal effects in animal studies, but no available human data.
It comes in category B. It is considered as safe drug. But not established as totally safe. You should use the category A drugs, whenever available.
Currently, no antidepressant medications are classified in pregnancy category B. Wellbutrin (bupropion) is the only antidepressant that was classified by the FDA in pregnancy category B, in the past. However, it has now been assigned by the FDA to category C. Fluoxetine, desipramine, phenelzine, sertraline, trazodone, nefazodone, venlafaxine, and mirtazapine by the FDA are classified in pregnancy category C. Paroxetine, amitriptyline, imipramine, and nortriptyline are classified iby the FDA in pregnancy Category D with positive evidence of human fetal risk.
category C during the first trimester and category D during the second and third trimesters.
Valium has been assigned to pregnancy category D by the FDA. so it means when there is pregnancy, so this drug should be take according to physician or pharmacist instructions, otherwise would cause increased risk of congenital malformations and other developmental abnormalities in fetus.