Mescaline is 3,4,5-trimethoxy-phenethylamine. Its structure is similar to the neurotransmitter dopamine and the amino acids phenethylamine and phenylalanine. Its stimulant effects come from its action on the dopaminergenic nervous system. However, its psychedelic effects arise from its action on the 5HT2A receptors of the serotonergic nervous system. In this regard, it is most likely a direct agonist of these sites.
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