When a medication molecule is protein bound, that maolecule cannot be used to create a clinical effect. Therefore, a medication that is HIGHLY protein bound does not leave a very high percentage of medication available for clinical effect.
Yes it is, therefore you need to be careful when taking other protein bound medications.
If a medication is protein-bound (i.e. albumin), they are not available for metabolism. Therefore, the more the drug is bound to protein, the less is metabolized.
yes
The segments of DNA that are loosly bound to protein are called Chromatin.
All cephalosporins are time-dependent except ceftriaxone b/c it's highly protein-bound. Hope that helped.
protein
GDP. Guanine diphosphate. Then the protein is phosphorylated and undergoes a conformational change in concert with its docking with the G protein linked receptor.
amino acids together in a protein
These membrane bound sacs are called vesicles.
A drug bound to a protein is an active drug
Only the free, unbound drug is active
Yes, where? The first R in 'RER' stands for rough as in 'rough endoplasmic reticulum'. Compare this to 'SER' - smooth endoplasmic reticulum. Yes, the rough designation reflects the existence of endoplasmic bound ribosome entities/particles that are the main sites of cellular protein synthesis.