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What does a m-protein spike in the gamma region of the protein electrophoresis indicate?
Wiki User
∙ 14y ago
Directly from the AAFP, 1 Jan 05,.several disease states cause a homogenous spike-like peak in a focal region of the gamma-globulin zone of the SPEP.In the interpretation of SPEP, most attention focuses on the gamma region, composed predominantly of the IgG type, however a single spike can occur in the alpha2, and beta regions in patients with multiple myeloma. Monoclonal gammopathies are associated with a clonal process that is malignant or potentially malignant. Multiple myeloma should be ruled out with a bone marrow biopsy, and diagnosis requires 10-15% plasma cell involvement and M-protein level is usually >3g/dL. Hope this sheds some light on the subject. Carl Weathers, RN MCG, Augusta, GA.
Wiki User
∙ 14y ago
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How does EMSA electromobility shift assay measure whether the protein bends DNA?
EMSA measures protein-DNA binding by observing the mobility shift of the DNA-protein complex in a gel electrophoresis system. When a protein binds to DNA, the complex migrates more slowly in the gel due to its larger size and altered shape. This shift in mobility indicates protein-induced bending or conformational changes in the DNA.
What is th blue dye added to the sample before the electrophoresis is performed?
In biochemistry labs, the traditional answer for a protein gel (polacrylamide gel electrophoresis) is bromphenol blue. For a DNA gel (agarose gel electrophoresis), traditionally the same dark blue dye bromphenol blue was combined with the lighter, slower migrating blue dye xylene cyanol. Oftentimes nowwe only use the bromphenol blue, or even substitute for it with Orange G, which is a UV-transparent dye that more easily enables the visualization of smaller molecular weight nucleic acids that migrate in the same region.
The region of a protein that binds a ligand?
The region on a protein that binds a ligand is known as the binding site. This site is typically composed of specific amino acids that interact with the ligand through various chemical bonds and molecular interactions. The binding of the ligand to the protein's binding site is crucial for the protein's function and activity.
Protein strands that attach to the centromere region during M-phase of cell cycle?
During Metaphase the protein strands that attach to the centromere region are called spindle fibres.
A region of the dna molecule that stores instructions for a protein is called a?
A region of the DNA molecule that stores instructions for a protein is called a gene. Genes are the basic unit of heredity and provide the code for creating proteins through a process called transcription and translation.
What do close flux lines indicate?
There is more magnetic force in that region on a particle.
How do you determine which region to shade to indicate the solution set of a system linear equation?
3
Which type of transporters is used to move a molecule from a region of low concentration traction to a region of high concentration?
protein molecules in the cell membrane
What is the region in the nucleus that produces tiny cell particles needed in protein synthesis?
The region in the nucleus that produces tiny cell particles needed in protein synthesis is the nucleolus. The nucleolus is responsible for assembling ribosomal subunits, which are essential for synthesizing proteins in the cell.
Is a gene a distinct region of a long protein molecule?
No, a gene is not a distinct region of a long protein molecule. A gene is a specific sequence of DNA that contains the instructions for making a particular protein or RNA molecule. Genes are segments of DNA that are transcribed into RNA and translated into proteins. Proteins are made up of a chain of amino acids, which are encoded by the sequence of nucleotides in a gene.
What is a region in the nucleus that produces tiny cell particles needed in protein synthesis?
chromosomes
Why was the rest of the world so concerned about the war and the region in general durning the 1970 and 1980?
Please indicate which region you are asking about. Viet Nam? Afghanistan? Israel?
