Directly from the AAFP, 1 Jan 05,.several disease states cause a homogenous spike-like peak in a focal region of the gamma-globulin zone of the SPEP.In the interpretation of SPEP, most attention focuses on the gamma region, composed predominantly of the IgG type, however a single spike can occur in the alpha2, and beta regions in patients with multiple myeloma. Monoclonal gammopathies are associated with a clonal process that is malignant or potentially malignant. Multiple myeloma should be ruled out with a bone marrow biopsy, and diagnosis requires 10-15% plasma cell involvement and M-protein level is usually >3g/dL. Hope this sheds some light on the subject. Carl Weathers, RN MCG, Augusta, GA.
In biochemistry labs, the traditional answer for a protein gel (polacrylamide gel electrophoresis) is bromphenol blue. For a DNA gel (agarose gel electrophoresis), traditionally the same dark blue dye bromphenol blue was combined with the lighter, slower migrating blue dye xylene cyanol. Oftentimes nowwe only use the bromphenol blue, or even substitute for it with Orange G, which is a UV-transparent dye that more easily enables the visualization of smaller molecular weight nucleic acids that migrate in the same region.
giology
It is called an active site (or region).
a region of the DNA molecule that stores instructions for a protein is called a
No. It is a distinct region of a DNA molecule.
The region of chromosome that is generally thought of as the unit of function is the "gene". Genes are composed of both a "coding region"--that sequence that tells the cell's machinery what the protein will be--and a "regulatory" region, which tells the cell when to turn on the coding region to make the protein.
EMSA does not measure if protein bends to DNA. It does measure what proteins bind to a specific region of DNA (usually a promoter region). You can use a supershift to determine exactly what protein is binding to the specific DNA region.
During Metaphase the protein strands that attach to the centromere region are called spindle fibres.
There is more magnetic force in that region on a particle.
3
The promoter is a nontranscribed region of a gene.
The region in the nucleus that produces tiny cell particles needed in protein synthesis is the nucleolus. It is responsible for making the small and large subunits of ribosomes.