It Caused Unexpected Damage To The Babies Of Thousands Of Pregnant Women.
There are quite a few advantages of human testing. By testing on humans doctors and researchers are able to directly see side affects.
The chemical formula of thalidomide is C13H10N2O4.
Thalidomide was supposed to be an effective sedative for pregnant women, but thalidomide caused birth defects and peripheral neuropathy.
Dark Remedy: The Impact of Thalidomide and Its Revival as a Vital Medicine by Rock Brynner and Trent D. Stephens Suffer the Children: The Story of Thalidomide Tough Cookie: The Less Than Virtuous Tale of a Thalidomide Mum by Sheila Mottley Thalidomide and the Power of the Drug Companies (A Penguin special) by Robert Nilsson and Henning Sjostrom Dark Remedy: The Impact of Thalidomide and Its Revival as a Vital Medicineby Rock Brynner and Trent D. Stephens Suffer the Children: The Story of Thalidomide Tough Cookie: The Less Than Virtuous Tale of a Thalidomide Mum by Sheila Mottley Thalidomide and the Power of the Drug Companies (A Penguin special) by Robert Nilsson and Henning Sjostrom
through blood testing
Because it failed to test the drug for its affects on developing embryos, even though it was targeted to be given to pregnant mothers to prevent morning sickness.
Thalidomide was before used to prevent pregnancy nausea (it was also later discovered that it caused birth defects and was thus banned), but after more research and testing they discovered the positive effects it had on patients with Hansen's disease/Leprosy, and the drug was reintroduced (women have to take a pregnancy test before having it prescribed)
Thalidomide regulates the immune response by suppressing a protein, tumor necrosis factor alpha.
Pro: living organism model Con: violates the animal's rights inefficient and ineffective, their anatomy and biological reactions are not the same (look up the thalidomide tragedy)
Make objective decisions about the validity of the hypotheses.
Thalidomide was developed by the German pharmaceutical company Chemie Grünenthal in the 1950s. It was marketed as a sedative and antiemetic medication before its teratogenic effects became apparent.