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ITP--immune thrombocytopenic purpura. Your body destroys platelets, basically... it can be chronic or something set off by an immune reaction to a virus, say (more common in children). You wouldn't have clotting problems, but bleeding/bruising problems. Many people with ITP feel fatigued and link it to their platelet levels, though it is not currently considered a symptom and there is no accepted medical explanation for why this would happen.

The Platelet Disorder Support Association says this on their FAQ:

A : Many people with ITP find they have a problem with fatigue. However, the cause of this fatigue is not well understood. In addition to general fatigue that may be associated with being ill, the treatments for ITP can contribute to fatigue by disrupting the sleep cycle and placing other types of stress on the body. http://www.itppeople.com/FAQAdults.htm (as of 7.26.09)

See http://www.pdsa.org/itp-information/index.html for more general information about ITP.

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Q: What could being extremely tired all the time and having a very low platelet count but not having any clotting problem possibly be?
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