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Treponema pallidum is the organism responsible for syphilis. So, unprotected sex with someone can pass on the disease.

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Name some of the microorganisms that are difficult to culture under laboratory conditions?

Some examples of microorganisms that are challenging to culture in a lab are Mycobacterium leprae, Treponema pallidum (the causative agent of syphilis), and certain types of archaea that live in extreme environments. These organisms have specific growth requirements that are difficult to replicate outside of their natural habitats.


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