What are Factors affecting solubility of pharmaceutical substances?
Factors affecting solubility of pharmaceutical substances include the chemical structure of the compound, pH of the solvent, temperature, presence of co-solvents or surfactants, and particle size. These factors can influence how well a drug dissolves in a solvent or biological fluid, impacting its bioavailability and efficacy. Understanding and manipulating these factors is important in the formulation and design of pharmaceutical products.