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What are Factors affecting solubility of pharmaceutical substances?
Factors affecting solubility of pharmaceutical substances include the chemical structure of the compound, pH of the solvent, temperature, presence of co-solvents or surfactants, and particle size. These factors can influence how well a drug dissolves in a solvent or biological fluid, impacting its bioavailability and efficacy. Understanding and manipulating these factors is important in the formulation and design of pharmaceutical products.
What are the factors affecting strength of tablets?
Factors affecting the strength of tablets include the type and concentration of binding agents used, the compression force applied during manufacturing, the particle size and distribution of the active ingredient, and the presence of any excipients that can affect tablet hardness. Other factors can include moisture content, temperature during compression, and the presence of any lubricants or glidants.
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