What are the effects of temperature on stability of drug?

Answer 1

The stability of a drug is the ability of the drug to maintain its chemical, physical, therapeutic and toxicological properties throughout its shelf life. Often times environmental and other unexplainable factors affect the stability of drugs by causing degradation of either the active ingredient of the drug product or the excipients, reducing the bioavailability of the drug or changing the physical appearance of the drug.

Answer 2

The effect of temp. on drug stability follows rule of thump .in other words as the temp. increase ,the degradation processes of the drug or drug material will increase. as the temp. raise by 10o c, the degradation processes doubled. consequently , may a hazard bi-product may be formed and affect the health.

abdulghafoor al-turkistani

college of pharmacy

king saud university

Answer 3

moisture increases the stability by increasig the degradation of mol;