answersLogoWhite

0


Best Answer

Gelatin capsule can be used to mask the taste of drugs and make the drug easier to swallow. There is no need to compact the material together so the material can be directly filled inside. The material can be filled multiple so that a unique delivery system can be designed within the capsule. As automatic filling machines are used to pump liquids with poorly-soluble drugs dissolved in them into hard shell capsules, it can help improve the content uniformity of these drugs. Hard shell capsules can also be used for modified-release formulations.

User Avatar

Wiki User

6y ago
This answer is:
User Avatar
More answers
User Avatar

Wiki User

6y ago

Gelatin capsule have a low bulk density so bulky substances may need granulation before the filing process. Capsule filling machines also create tablets slower than tablet presses. Gelatin capsules are also not suitable for very soluble may be suddenly released in the stomach causing irritation. Gelatin capsules are also not that physically stable. They should have an equilibrium moisture content of 13-16%. These capsules are also prone to cross-linking when they are exposed to traces of aldehydes or stored for too long in extreme temperature or humidity. They will ultimately become water-insoluble. HPMC-based capsules can be used to prevent this from happening.

This answer is:
User Avatar

Add your answer:

Earn +20 pts
Q: What are the disadvantages of using gelatin capsule?
Write your answer...
Submit
Still have questions?
magnify glass
imp
Related questions

Where to buy empty gelatin capsule in Melbourne Australia?

eat some jello, then the next time you use the bathroom, there's your gelatin capsule.


Difference between hard gelatin capsule and soft gelatin capsule?

Hard gelatin capsules have a body and a cap. They are cylindrical in shape and are sealed after they have been filled with medications. Soft gelatin capsules are just one single unit after the two halves have been sealed. They also consist of liquids and are prepared from plasticizer and gelatin.


What are acceptable quality limits in soft gelatin capsule?

60mints


What is a gelatinlike capsule?

A gelatin-like capsule is a type of capsule typically made with gelatin and used to contain medication or supplements. It is usually smooth, transparent, and easy to swallow. These capsules dissolve quickly in the stomach, releasing the contents for absorption.


I am taking cod liver oil which comes in capsule form what is the capsule made off.?

If you check the ingredients, most capsules are made of gelatin and glycerin.


Do you open capsules or swallow them whole?

You swallow them whole. The capsule is made of gelatin and will dissolve in your stomach.


Does lyrica have halal gelatine?

Lyrica, your product ( Pregabalin ) have a hard gelatin Capsule. Is hard gelatin capsule a halal of not? I really want to know about that. Please give me answer back because I want to give this drugs for treating islamic patient who suffered from neuropathic pain


What is Difference between hard soft gelatin capsule?

Both of these types of capsules share the main ingredient Gelatin: Gelatin is a protein produced by partial hydrolysis of collagen extracted from the boiled bones, connective tissues, organs and some intestines of animals such as domesticated cattle, pigs, poultry, goats, dogs, cats, (from animal shelters that have been put down) and horses. Gelatin melts to a liquid when heated and solidifies when cooled again. If gelatin is put into contact with cold water, very little of the material dissolves. The solubility of the gelatin is determined by the method of manufacture. Typically, gelatin can be dispersed in a relatively concentrated acid. (stomach acids) Gelatin also contains up to 15% Glutamic acid (MSG) by weight as a preservative (antibiotic) The difference between Soft Gelatin and Hard Gelatin capsules is the amount of plasticizer chemical that has been added to the formulation. More Plasticizer, more rubbery, and pliable the capsule will be.


How do you make soft candies using gelatin?

Yes gelatin is sticky


What will melt a gelatin and glycerin pill capsule stuck in your throat?

Small, continuous sips of warm water.


What is the function of capsule?

The function of a capsule is to contain the active ingredient and any excipient materials in a medicine. Typically, capsules are made of a Gelatin material and dissolves quickly to speed delivery of the medicine.


Why was a gelatin capsule choose to be used on a paintball?

Because maybe any other type of substances would not have broken as easily.