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What is the difference between penicillin family and sulfonamides?
what is the difference between sulfonamides and penicillin
What is the mechanism of action of sulfonamides?
Sulfonamides inhibit dihydropteroate synthetase so that the bacteria's nucleotide synthesis is inhibited.
Can sulfonamides cause cholestasis?
Yes
What can Bacterial Diseases be treated with?
Antibiotics or sulfonamides.
What is Tetracycline and penicillin and cephalosporin and sulfonamides and aminoglycosides?
Antibiotics
What are sulfonamides used for?
Sulfonamides are a type of antibiotic commonly used to treat bacterial infections such as urinary tract infections, respiratory tract infections, and skin infections. They work by inhibiting the growth of bacteria by blocking their ability to produce folic acid, which is essential for their survival. It is important to note that sulfonamides are not effective against viral infections.
What pathway do sulfonamides inhibit?
Sulfonamides inhibit the synthesis of dihydropteroate which is a precursor for the synthesis of tetrahydrofolic acid. This inhibition disrupts the production of nucleic acids in bacteria, leading to bacteriostatic effects.
What are the problems with sulfonamides and breastfeeding?
Sulfonamides pass into breast milk and may cause liver problems, anemia, and other problems in nursing babies whose mothers take the medicine.
Should sulfonamides be taken on an empty stomach?
Yes, Sulfonamides should be taken on an empty stomach 1 hour before or 2 hours after a meal. IF you do have GI upset then eat a small snack.
Are sulfonamides synthetic?
Yes, sulfonamides are synthetic antimicrobial agents. They were among the first antibiotics developed and are derived from sulfanilamide, a compound that mimics para-aminobenzoic acid (PABA) and inhibits bacterial growth by interfering with folic acid synthesis. Since their introduction in the 1930s, sulfonamides have been widely used in treating various bacterial infections.
How sulfonamides cause kidney stone?
Sulfonamides are likely to precipitate in urine resulting in crystalluria.If the patient does not take adequate amounts of water(6-8 glasses/day) these are likely to aggregate into kidney stones
How Sulfonamides work on human body?
Sulfonamides are a class of antibiotic - the first class of useful antibiotic, in fact. They work by inhibiting the production of folate by bacteria. Because humans cannot make their own folate (we must eat folate produced by other organisms), sulfonamides do not affect human cells. Folate is necessary for the production of DNA and RNA, so inhibiting its production in bacterial cells stops the bacterial cells from dividing. Because sulfonamides to not directly kill the bacteria, only stop their spread, they are called bacteriostatic.
