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If you are talking about the relationship of cell size with cell volume..The smaller the cell, the healthier. This is because cell volume is expressed in units to the third power. Cell surface area is expressed in units to the second power. Therefore, cell volume grows exponentially quicker than cell surface area. Smaller cells are at an advantage, so they can transport enough substances through its membranes to support its volume.

Source: I'm a sophomore in high school, taking Biology we learned this in the beginning of the school year.

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