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There doesn't seem to be a medication per say, but there are IgE therapies. Humanized monoclonal anti-IgE antibodies have been developed. To date, only one study by Leung et al has examined the role of anti-IgE in food allergy. In their double-blind, placebo-controlled study on patients with peanut allergy, patients were randomly assigned to receive monthly subcutaneous injections of placebo or one of three doses of the anti-IgE TNX-901 (Tanox Biosystems, Houston, Texas, USA), 150, 300 and 450 mg. TNX-901 at a dose of 450 mg increased the threshold for sensitivity to peanut to a level that confers protection against most unintended peanut ingestions in 76% of patients. The drug was well tolerated. Further investigation using this antibody was discontinued after an agreement among pharmaceutical companies that were involved in the development of anti-IgE therapies.

Anti-IgE therapy may eventually prove to be useful as an adjunct to allergen avoidance, and may prove to be protective against other food Allergies in the same individuals. It may, however, have to be administered indefinitely.

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15y ago

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