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Although there are no severe health issues with expired aspirin, it may cause stomach irritation or pain, and have a reduced potency. If possible, you should discard any expired aspirin and buy a new bottle.

Aspirin is a relatively stable compound that does not break down readily in dry air, but over time contact with moisture will break it down into acetic and salicylic acids. A purported chemist on Epinions.com mentions that aspirin was inspired by the traditional use of salicylic acid extracted from willow bark to reduce pain and inflammation, but this often damaged the mucous membranes of the mouth and esophagus, and caused hemorrhaging of the stomach lining.

Pharmaceutical scientists discovered that by modifying the compound slightly, they could produce a safer form of the acid called acetylsalicylic acid that did not cause any damage. However, very old aspirin can break down into salicylic acid and thus cause irritation of the stomach. This is normally accompanied by a vinegar-like odour from the bottle when you open it.

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9y ago
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7y ago

Let's say that it's just not wise to use expired medications. The reason is that they can lose their potency and are then not as effective as they should be and we might be inclined to take more than is necessary. This is your health we are dealing with ... never compromise on any medication as far as your health is concerned ... never.

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13y ago

Yes. The only difference is the medicine in the excedrin (acetaminophen, asprin) has degraded and has become less active, thus the effect might not be as strong. Either way, you'll be fine.

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11y ago

No, It is not safe to take any expired medicine..

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Q: Is it safe to take expired Adderall?
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